-
Media gallery
Media gallery
-
Media gallery
Media gallery
-
Media gallery
Media gallery
Zebra ZD621 Thermal Transfer Printer with Cutter | 300 DPI, USB, USB Host, Ethernet, Serial, Bluetooth 5, EZPL
-
Future-ready architecture: Built on Zebra’s latest platform, the ZD621 supports evolving applications, new tools, and continuous performance upgrades to keep you ahead.
-
Versatile and configurable: From RFID to healthcare and media-handling upgrades, it’s adaptable to your workflow with field-installable options that scale with your needs.
-
Intelligent and intuitive control: The optional full-color touchscreen and Print DNA software suite enable easy setup, remote management, and consistent productivity.
-
Effortless system integration: With full support for EPL, ZPL, and Virtual Devices, ZD621 integrates smoothly into existing setups without workflow disruptions.
-
Advanced security with PrintSecure: Defend against downtime and cyber threats with real-time monitoring and enterprise-grade protection built into every device
-
Overview
-
Specifications
-
FAQ
-
User Guides
-
Reviews
Step up to premium performance with the ZD621—Zebra’s most advanced 4-inch desktop printer built for high-demand, long-term use. Whether upgrading from GX or ZD500 models or starting new, the ZD621 delivers best-in-class features, seamless integration, and enterprise-level security. With flexible models for standard, RFID, and healthcare environments, it’s engineered to meet today's needs and tomorrow’s challenges—effortlessly.
-
Future-ready architecture: Built on Zebra’s latest platform, the ZD621 supports evolving applications, new tools, and continuous performance upgrades to keep you ahead.
-
Versatile and configurable: From RFID to healthcare and media-handling upgrades, it’s adaptable to your workflow with field-installable options that scale with your needs.
-
Intelligent and intuitive control: The optional full-color touchscreen and Print DNA software suite enable easy setup, remote management, and consistent productivity.
-
Effortless system integration: With full support for EPL, ZPL, and Virtual Devices, ZD621 integrates smoothly into existing setups without workflow disruptions.
-
Advanced security with PrintSecure: Defend against downtime and cyber threats with real-time monitoring and enterprise-grade protection built into every device
Q1: What is this ZD621 printer model?
The ZD621 Thermal Transfer is a premium 4-inch desktop printer, part of Zebra’s flagship ZD600 series. It’s built for maximum reliability, best-in-class security, and flexible printing for demanding labeling applications — day in and day out.
✅ Q2: What does ‘Thermal Transfer’ mean?
Unlike direct thermal, thermal transfer printing uses a ribbon to bond ink to the label surface.
✔️ Ideal for labels that need to last longer
✔️ Resists heat, sunlight, and chemicals
✔️ Works with a variety of label materials (paper, synthetic)
✅ Q3: What resolution does it offer?
This ZD621 prints at 300 dpi, ensuring crisp, high-quality text, barcodes, and graphics — perfect for detailed or small labels.
✅ Q4: What connectivity does it include?
You have flexible connections to fit almost any setup:
USB 2.0
USB Host (connect peripherals)
Ethernet
Serial
Bluetooth Low Energy (BTLE5)
This allows easy integration into your wired or wireless environment.
✅ Q5: What does the ‘Cutter’ do?
This model includes a built-in label cutter, letting you print and automatically cut individual labels, tags, or receipts.
✔️ Great for batch printing
✔️ Speeds up workflows
✔️ Cleaner label edges
✅ Q6: Is it easy to operate?
Yes — the ZD621 is designed for simplicity:
Print DNA software makes setup and management straightforward.
✅ Q7: What security features does it have?
Zebra’s PrintSecure, part of the Print DNA suite, helps protect your printer and network:
✔️ Secure connections
✔️ Proactive threat monitoring
✔️ Data encryption
✔️ Endpoint protection
✔️ Helps prevent costly downtime from IoT attacks
-
$1,610.43 - Regular price
- $1,050.64
- Sale price
- $1,050.64
- Unit price
- / per
-
$1,610.43 - Regular price
- $1,050.64
- Sale price
- $1,050.64
- Unit price
- / per
Get same day shipping on orders placed before 3 PM EST.
Couldn't load pickup availability
-
Free Ground Shipping Sign in to unlock FREE ground shipping for all users!
-
30 day Return Policy

-
Free One Year Warranty

-
Security Transaction

-
Net 30 Terms


Have a question?
Notified by email when this product becomes available
Get 5% Off your First Order
Click to get couponReal Support from Real People
Contact us for helpFree 30-Day Returns
Return PolicyYOU MAY ALSO LIKE
BEST SELLING PRODUCTS
Zebra DS2278-SR6U2100PRW Cordless Handheld Barcode Scanner | USB Kit with Cradle, Black
-
- Regular price
- $190.00
- Sale price
- $190.00
- Unit price
- / per
Zebra DS9308-SR00004ZZCN Presentation Barcode Scanner | 1D/2D, Omni
-
- Regular price
- $129.00
- Sale price
- $129.00
- Unit price
- / per
Zebra DS4608-SR7U2100SGW Handheld Imager | 1D/2D, General Purpose, Cable & Stand, Multi-Interface, Standard Range, USB
-
- Regular price
- $168.00
- Sale price
- $168.00
- Unit price
- / per
Zebra ZD421 Direct Thermal Barcode Label Printer | 203 dpi, USB (ZD4A042-D01M00EZ)
-
- Regular price
- $390.00
- Sale price
- $390.00
- Unit price
- / per
Zebra ZD421 Direct Thermal Desktop Printer | 203 dpi, 4" Print Width, Wired USB & Ethernet (ZD4A042-D01E00EZ)
-
$998.00 - Regular price
- $489.00
- Sale price
- $489.00
- Unit price
- / per
Zebra DS3678-ER Ultra-Rugged Cordless Barcode Scanner | 2D/1D Linear Imager, Extended Range, Bluetooth, FIPS, Cradle, Power Supply
-
- Regular price
- $639.00
- Sale price
- $639.00
- Unit price
- / per
Zebra DS3678-SR0F003VZWW Ultra-Rugged Cordless Barcode Scanner | 2D/1D Linear Imager, Bluetooth, FIPS, Cradle & Power Supply
-
$599.00 - Regular price
- $519.00
- Sale price
- $519.00
- Unit price
- / per
Zebra, ZD421 Thermal Transfer Desktop Printer | 300 dpi, 4" Print Width, USB/Ethernet (ZD4A043-301E00EZ)
-
- Regular price
- $545.00
- Sale price
- $545.00
- Unit price
- / per












