Media gallery
Media gallery
Citizen CL-S521II-EPUBK-C Direct Thermal Barcode Label Printer with Ethernet, USB & Auto Cutter Media gallery
Media gallery
Citizen CL-S521II-EPUBK-C Direct Thermal Barcode Label Printer with Ethernet, USB & Auto Cutter
Citizen CL-S521II-EPUBK-C Direct Thermal Barcode Label Printer with Ethernet, USB & Auto Cutter
• 203 DPI direct thermal printing at 6 inches per second delivers fast label output for high-volume shipping and inventory operations
• Premium Ethernet, USB, and serial connectivity with ZPL2, Datamax, and EPL2 emulation ensures compatibility with existing systems
• All-metal Hi-Lift mechanism and integrated auto cutter handle labels and wristbands up to 4.6 inches wide with minimal maintenance
• 32-bit RISC processor provides instant first label printing and processes typical courier labels in just one second
• Vertical Hi-Open case design enables quick media loading without increasing desktop footprint or requiring lateral clearance
-
Overview
-
Specifications
-
FAQ
-
User Guides
-
Reviews
The Citizen CL-S521II-EPUBK-C is an industrial desktop label printer engineered for enterprise environments requiring reliable, high-speed barcode and label production. This direct thermal printer combines 203 DPI resolution with 6 inches per second printing speed to handle demanding workflows in shipping, receiving, inventory management, and healthcare identification applications. The premium network-enabled model features Ethernet connectivity alongside USB and serial interfaces, making it suitable for networked environments where multiple workstations need shared printing access.
Built on Citizen's proven Hi-Lift all-metal print mechanism, the CL-S521II accommodates media widths from 0.5 to 4.6 inches and supports roll capacities up to 5 inches in diameter. The integrated auto cutter eliminates manual label separation, while onboard ZPL2, Datamax, and EPL2 emulations ensure drop-in compatibility with existing label design software and ERP systems. A powerful 32-bit RISC processor delivers virtually instant first label output, reducing wait times in time-sensitive operations. The vertical Hi-Open case design allows operators to reload media quickly without disrupting the printer's desktop footprint.
Best For
The CL-S521II-EPUBK-C serves enterprise operations requiring networked label printing with auto-cut functionality across multiple applications:
- Distribution center shipping: Print compliance labels, packing slips, and carrier-specific barcode labels at 6 IPS to keep pace with high-volume fulfillment
- Healthcare specimen tracking: Generate patient wristbands and specimen labels with precise 203 DPI barcodes for laboratory and pharmacy workflows
- Retail inventory management: Produce shelf tags, price labels, and asset identification tags with instant first label output for floor staff efficiency
- Manufacturing work-in-process: Create durable direct thermal labels for production tracking, quality control, and parts identification in industrial environments
- Multi-station warehouse operations: Deploy as networked printers via Ethernet for shared access across receiving, put-away, and picking workstations
Key Features
- 203 DPI direct thermal printing technology produces crisp 1D/2D barcodes, text, and graphics without ribbon consumables
- 6 inches per second maximum print speed with instant first label output processes typical courier labels in one second
- Premium Ethernet interface supports up to 1 Gbps network speeds for integration into enterprise print server environments
- Onboard ZPL2, Datamax, and EPL2 emulations plus CBI BASIC Interpreter enable compatibility with legacy and current label software
- All-metal Hi-Lift mechanism with adjustable sensor handles standard labels, specialty tags, and pediatric/adult medical wristbands
- Integrated auto cutter automatically separates labels for walk-up printing without manual tearing or waste
- Variable media width support from 0.5 to 4.6 inches accommodates shipping labels, retail tags, and asset identification formats
- 32-bit RISC processor with internal power supply eliminates external adapters and delivers reliable high-throughput performance
Quick Specs
| Print Method | Direct Thermal |
| Resolution | 203 DPI |
| Print Speed | 6 inches per second (maximum) |
| Print Width | 104 mm (4.1 inches) maximum |
| Media Width | 0.5 to 4.6 inches (variable) |
| Media Capacity | Up to 5 inches roll diameter |
| Connectivity | Premium Ethernet (1 Gbps), USB, Serial |
| Emulation | ZPL2, Datamax, EPL2, CBI BASIC Interpreter |
| Processor | 32-bit RISC CPU |
| Cutter | Integrated auto cutter (included) |
| Barcode Support | Code 39, UPC-A/E, Interleaved 2 of 5, Code 128, EAN-13/8, CODABAR, UCC/EAN128, PDF417, Data Matrix, QR Code, MaxiCode, and more |
| Print Mechanism | Durable all-metal Hi-Lift design |
| Case Design | Vertical Hi-Open (no footprint increase when open) |
| Power Supply | Internal mains power supply |
| Weight | 10.55 lbs |
| Color | Gray casing |
| Model Code | CL-S521II-EPUBK-C (E=Ethernet Premium, U=USB, BK=Black/Gray, C=Cutter) |
| Color | Gray |
| Connection Type | Ethernet, USB |
What types of operations is the Citizen CL-S521II-EPUBK-C best suited for?
How does the CL-S521II-EPUBK-C compare to other models in the Citizen CL-S521 series?
Is the CL-S521II-EPUBK-C worth the investment compared to lower-cost thermal printers?
What systems and software is the CL-S521II-EPUBK-C compatible with?
What types of labels and media can the CL-S521II-EPUBK-C handle?
How fast does the CL-S521II-EPUBK-C print compared to typical desktop label printers?
Does the auto cutter require maintenance or replacement parts?
What is the expected lifespan and duty cycle rating of the CL-S521II-EPUBK-C?
-
$981.75 - Regular price
- $646.78
- Sale price
- $646.78
- Unit price
- / per
-
$981.75 - Regular price
- $646.78
- Sale price
- $646.78
- Unit price
- / per
1–2 weeks lead time may apply
Couldn't load pickup availability
-
Free Ground Shipping Sign in to unlock FREE ground shipping for all users!
-
30 day Return Policy

-
Free One Year Warranty

-
Security Transaction

-
Net 30 Terms


Have a question?
Notified by email when this product becomes available
YOU MAY ALSO LIKE
BEST SELLING PRODUCTS
Zebra DS4608-SR7U2100SGW Handheld Imager | 1D/2D, General Purpose, Cable & Stand, Multi-Interface, Standard Range, USB
-
- Regular price
- $168.00
- Sale price
- $168.00
- Unit price
- / per
Zebra ZD421 Direct Thermal Desktop Printer | 203 dpi, 4" Print Width, Wired USB & Ethernet (ZD4A042-D01E00EZ)
-
$998.00 - Regular price
- $489.00
- Sale price
- $489.00
- Unit price
- / per
Honeywell Voyager XP 1472G Wireless Barcode/Area-Imaging Scanner Kit | 2D/1D/PDF/Postal, including a USB cable and a base
-
- Regular price
- $215.00
- Sale price
- $215.00
- Unit price
- / per
Zebra DS3678-SR Cordless Ultra-Rugged Barcode Scanner - Standard Range 1D/2D, FIPS USB Kit
-
$599.00 - Regular price
- $519.00
- Sale price
- $519.00
- Unit price
- / per
Zebra DS8178-SR Wireless Bluetooth Barcode Scanner | 1D/2D Imager, Includes Cradle & USB Cord
-
- Regular price
- $359.00
- Sale price
- $359.00
- Unit price
- / per
Zebra ZT23142-D01000FZ ZT231 4 Inch Direct Thermal Industrial Printer - 203 DPI, Tear-Off, USB, Serial, Ethernet, Bluetooth Low Energy, USB Host, US Cord
-
- Regular price
- $939.00
- Sale price
- $939.00
- Unit price
- / per
Zebra ZT41143-T010000Z ZT411 Industrial Label Printer - Thermal Transfer, 4-Inch Print Width, 300 dpi, Serial, USB, 10/100 Ethernet, Bluetooth 4.1/MFi, USB Host, US Cord
-
- Regular price
- $1,499.99
- Sale price
- $1,499.99
- Unit price
- / per
Zebra Symbol DS8178-SR 2D/1D Wireless Bluetooth Barcode Scanner/Imager, Includes Cradle and USB Cord (Upgraded Model of DS6878-SR)
-
- Regular price
- $349.00
- Sale price
- $349.00
- Unit price
- / per












